Publications

Shu Lab Publication Record

Use the table to explore our publication record, imported from PubMed. For a more complete listing of publications prior to 2012, visit our Google Scholar page: https://scholar.google.com/citations?user=IkhTUu4AAAAJ&hl=en
ProjectApplicationTitleAuthorsJournalYearPMID
ATPSBioassaysOne-incubation one-hour multiplex ELISA enabled by aqueous two-phase systemsTongdee M, Yamanishi C, Maeda M, Kojima T, Dishinger J, Chantiwas R, Takayama S.Analyst202032248215
Hanging drop/3D cultureMicrophysological SystemsStudying Adipose Tissue in the Breast Tumor Microenvironment In Vitro: Progress and OpportunitiesMertz D, Sentosa J, Luker G, Takayama S.Tissue Eng Regen Med202032939672
Hanging drop/3D cultureMicrophysological SystemsCancer Cell Invasion of Mammary Organoids with Basal-In PhenotypeParigoris E, Lee S, Mertz D, Turner M, Liu AY, Sentosa J, Djomehri S, Chang HC, Luker K, Luker G, Kleer CG, Takayama S.Adv Healthc Mater202032583612
ATPSBioassaysBiofabrication of phenotypic pulmonary fibrosis assaysYamanishi C, Robinson S, Takayama S.Biofabrication201931215521
NETsBiomaterialsAntimicrobial Microwebs of DNA-Histone Inspired from Neutrophil Extracellular TrapsSong Y, Kadiyala U, Weerappuli P, Valdez JJ, Yalavarthi S, Louttit C, Knight JS, Moon JJ, Weiss DS, VanEpps JS, Takayama S.Adv Mater201930698844
NETsBiomaterialsDNA-Based Biomaterials for ImmunoengineeringMaeda M, Kojima T, Song Y, Takayama S.Adv Healthc Mater201930516349
Misc./CollabControlled cellular microenvironmentRapid translocation of pluripotency-related transcription factors by external uniaxial forcesTopal T, Kim BC, Villa-Diaz LG, Deng CX, Takayama S, Krebsbach PH.Integr Biol (Camb)201930809641
Misc./CollabControlled cellular microenvironmentA Two-Pulse Cellular Stimulation Test Elucidates Variability and Mechanisms in Signaling PathwaysSumit M, Jovic A, Neubig RR, Takayama S, Linderman JJ.Biophys J201930782397
Misc./CollabControlled cellular microenvironmentDispersible hydrogel force sensors reveal patterns of solid mechanical stress in multicellular spheroid culturesLee W, Kalashnikov N, Mok S, Halaoui R, Kuzmin E, Putnam AJ, Takayama S, Park M, McCaffrey L, Zhao R, Leask RL, Moraes C.Nat Commun201930635553
Misc./CollabControlled cellular microenvironmentNonadhesive Alginate Hydrogels Support Growth of Pluripotent Stem Cell-Derived Intestinal OrganoidsCapeling MM, Czerwinski M, Huang S, Tsai YH, Wu A, Nagy MS, Juliar B, Sundaram N, Song Y, Han WM, Takayama S, Alsberg E, Garcia AJ, Helmrath M, Putnam AJ, Spence JR.Stem Cell Reports201930612954
NETsControlled cellular microenvironmentExtracellular Trap-Mimicking DNA-Histone Mesostructures Synergistically Activate Dendritic CellsWeerappuli PD, Louttit C, Kojima T, Brennan L, Yalavarthi S, Xu Y, Ochyl LJ, Maeda ML, Kim HS, Knight JS, Takayama S, Moon JJ.Adv Healthc Mater201931614077
ATPSMicro/nanofabricationStigmatic Microscopy Enables Low-Cost, 3D, Microscale Particle Imaging Velocimetry in Rehydrating Aqueous Two-Phase SystemsYamanishi C, Oliver CR, Kojima T, Takayama S.Front Chem201931179265
ATPSMicro/nanofabricationDetermination of Aqueous Two-Phase System Binodals and Tie-Lines by Electrowetting-on-Dielectric Droplet ManipulationKojima T, Lin CC, Takayama S, Fan SK.Chembiochem201930394637
Hanging drop/3D cultureMicrophysological SystemsA reproducible scaffold-free 3D organoid model to study neoplastic progression in breast cancerDjomehri SI, Burman B, Gonzalez ME, Takayama S, Kleer CG.J Cell Commun Signal201930515709
MicrofluidicsMicrophysological SystemsMicrophysiological systems modeling acute respiratory distress syndrome that capture mechanical force-induced injury-inflammation-repairViola H, Chang J, Grunwell JR, Hecker L, Tirouvanziam R, Grotberg JB, Takayama S.APL Bioeng201931768486
Misc./CollabMicrophysological SystemsA platform for artificial intelligence based identification of the extravasation potential of cancer cells into the brain metastatic nicheOliver CR, Altemus MA, Westerhof TM, Cheriyan H, Cheng X, Dziubinski M, Wu Z, Yates J, Morikawa A, Heth J, Castro MG, Leung BM, Takayama S, Merajver SD.Lab Chip201930810557
Misc./CollabBiomaterialsBudding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrilsSong Y, Michaels TCT, Ma Q, Liu Z, Yuan H, Takayama S, Knowles TPJ, Shum HC.Nat Commun201829844310
ATPSBioprintingMembraneless Compartmentalization Facilitates Enzymatic Cascade Reactions and Reduces Substrate InhibitionKojima T, Takayama S.ACS Appl Mater Interfaces201830179001
MicrofluidicsControlled cellular microenvironmentSteady Displacement of Long Gas Bubbles in Channels and Tubes Filled by a Bingham FluidZamankhan P, Takayama S, Grotberg JB.Phys Rev Fluids201830740583
MicrofluidicsMicrofluidic circuitsCapacitive coupling synchronizes autonomous microfluidic oscillatorsLesher-Pérez SC, Zhang C, Takayama S.Electrophoresis201829383730
MicrofluidicsMicrophysological SystemsPerspective: The promise of multi-cellular engineered living systemsKamm RD, Bashir R, Arora N, Dar RD, Gillette MU, Griffith LG, Kemp ML, Kinlaw K, Levin M, Martin AC, McDevitt TC, Nerem RM, Powers MJ, Saif TA, Sharpe J, Takayama S, Takeuchi S, Weiss R, Ye K, Yevick HG, Zaman MH.APL Bioeng201831069321
MicrofluidicsMicrophysological SystemsEngineering cell heterogeneity into organs-on-a-chipMertz DR, Ahmed T, Takayama S.Lab Chip201830040104
MicrofluidicsMicrophysological SystemsIntegration of Sensors in Gastrointestinal Organoid Culture for Biological AnalysisKim GA, Ginga NJ, Takayama S.Cell Mol Gastroenterol Hepatol201829928682
MicrofluidicsReproductive TechnologyCryopreservation and microfluidics: a focus on the oocyteSmith GD, Takayama S.Reprod Fertil Dev201832188545
Hanging drop/3D cultureMicro/nanofabricationDispersible oxygen microsensors map oxygen gradients in three-dimensional cell culturesLesher-Pérez SC, Kim GA, Kuo CH, Leung BM, Mong S, Kojima T, Moraes C, Thouless MD, Luker GD, Takayama S.Biomater Sci201728805850
Hanging drop/3D cultureMicrophysological SystemsBioengineering for intestinal organoid culturesKim GA, Spence JR, Takayama S.Curr Opin Biotechnol201728646678
Hanging drop/3D cultureMicrophysological SystemsDesigning 3-D Adipospheres for Quantitative Metabolic StudyAkama T, Leung BM, Labuz J, Takayama S, Chun TH.Methods Mol Biol201728244051
MicrofluidicsMicrophysological SystemsBuilding an experimental model of the human body with non-physiological parametersLabuz JM, Moraes C, Mertz DR, Leung BM, Takayama S.Technology (Singap World Sci)201728713851
MicrofluidicsMicrophysological SystemsCorrection: Cell, Isoform, and Environment Factors Shape Gradients and Modulate ChemotaxisChang SL, Cavnar SP, Luker KE, Takayama S, Luker GD, Linderman JJ.PLoS One201728291822
MicrofluidicsReproductive TechnologyApplication of microfluidic technologies to human assisted reproductionSmith GD, Takayama S.Mol Hum Reprod201728130394
MicrofluidicsReproductive TechnologyConcomitant differentiation of a population of mouse embryonic stem cells into neuron-like cells and schwann cell-like cells in a slow-flow microfluidic deviceRamamurthy P, White JB, Yull Park J, Hume RI, Ebisu F, Mendez F, Takayama S, Barald KF.Dev Dyn201727761977
ATPSBioassaysAqueous Two-Phase System Rehydration of Antibody-Polymer Microarrays Enables Convenient Compartmentalized Multiplex ImmunoassaysEiden L, Yamanishi C, Takayama S, Dishinger JF.Anal Chem201627808499
Hanging drop/3D cultureControlled cellular microenvironmentImaging Sensitivity of Quiescent Cancer Cells to Metabolic Perturbations in Bone Marrow SpheroidsCavnar SP, Xiao A, Gibbons AE, Rickelmann AD, Neely T, Luker KE, Takayama S, Luker GD.Tomography201627478871
NanochannelsDNA linearizationDynamic simulations show repeated narrowing maximizes DNA linearization in elastomeric nanochannelsHan M, Kim BC, Matsuoka T, Thouless MD, Takayama S.Biomicrofluidics201627965731
ATPSMicro/nanofabricationAqueous Two Phase System Assisted Self-Assembled PLGA MicroparticlesYeredla N, Kojima T, Yang Y, Takayama S, Kanapathipillai M.Sci Rep201627279329
Misc./CollabMicro/nanofabricationNanoparticle Assemblies into Luminescent Dendrites in Shrinking MicrodropletsKojima T, Hirai K, Zhou Y, Weerappuli P, Takayama S, Kotov NA.Langmuir201627571169
MicrofluidicsMicrophysological SystemsPharmacokinetic profile that reduces nephrotoxicity of gentamicin in a perfused kidney-on-a-chipKim S, LesherPerez SC, Kim BC, Yamanishi C, Labuz JM, Leung B, Takayama S.Biofabrication201627011358
MicrofluidicsMicrophysological SystemsOrganization of Endothelial Cells, Pericytes, and Astrocytes into a 3D Microfluidic in Vitro Model of the Blood-Brain BarrierWang JD, Khafagy el-S, Khanafer K, Takayama S, ElSayed ME.Mol Pharm201626751280
ATPSBioassaysRecent developments in multiplexing techniques for immunohistochemistryDixon AR, Bathany C, Tsuei M, White J, Barald KF, Takayama S.Expert Rev Mol Diagn201526289603
ATPSBioassaysHigh-yield isolation of extracellular vesicles using aqueous two-phase systemShin H, Han C, Labuz JM, Kim J, Kim J, Cho S, Gho YS, Takayama S, Park J.Sci Rep201526271727
ATPSBioassaysSystems for multiplexing homogeneous immunoassaysYamanishi CD, Chiu JH, Takayama S.Bioanalysis201526168258
ATPSBioassaysMicroscale 3D collagen cell culture assays in conventional flat-bottom 384-well platesLeung BM, Moraes C, Cavnar SP, Luker KE, Luker GD, Takayama S.J Lab Autom201525510473
MicrofluidicsBioassaysAn electrochemical-sensor system for real-time flow measurements in porous materialsBathany C, Han JR, Abi-Samra K, Takayama S, Cho YK.Biosens Bioelectron201525797850
Misc./CollabBioassaysA cost-effective fluorescence mini-microscope for biomedical applicationsZhang YS, Ribas J, Nadhman A, Aleman J, Selimović Š, Lesher-Perez SC, Wang T, Manoharan V, Shin SR, Damilano A, Annabi N, Dokmeci MR, Takayama S, Khademhosseini A.Lab Chip201526282117
Misc./CollabBiomaterialsElongation of fibers from highly viscous dextran solutions enables fabrication of rapidly dissolving drug carrying fabricsFrampton JP, Lai D, Lounds M, Chung K, Kim J, Mansfield JF, Takayama S.Adv Healthc Mater201525204273
ATPSBioprintingAqueous two-phase system-mediated antibody micropatterning enables multiplexed immunostaining of cell monolayers and tissuesFrampton JP, Tsuei M, White JB, Abraham AT, Takayama S.Biotechnol J201525046484
Misc./CollabBioprintingSurface-templated hydrogel patterns prompt matrix-dependent migration of breast cancer cells towards chemokine-secreting cellsKojima T, Moraes C, Cavnar SP, Luker GD, Takayama S.Acta Biomater201525463502
ATPSControlled cellular microenvironmentFormation and manipulation of cell spheroids using a density adjusted PEG/DEX aqueous two phase systemHan C, Takayama S, Park J.Sci Rep201526144552
Hanging drop/3D cultureControlled cellular microenvironmentMedia additives to promote spheroid circularity and compactness in hanging drop platformLeung BM, Lesher-Perez SC, Matsuoka T, Moraes C, Takayama S.Biomater Sci201526218124
Hanging drop/3D cultureControlled cellular microenvironmentModeling selective elimination of quiescent cancer cells from bone marrowCavnar SP, Rickelmann AD, Meguiar KF, Xiao A, Dosch J, Leung BM, Cai Lesher-Perez S, Chitta S, Luker KE, Takayama S, Luker GD.Neoplasia201526408255
MicrofluidicsControlled cellular microenvironmentOrgan-on-a-chip and the kidneyKim S, Takayama S.Kidney Res Clin Pract201526484042
MicrofluidicsControlled cellular microenvironmentA microfluidic model to study fluid dynamics of mucus plug rupture in small lung airwaysHu Y, Bian S, Grotberg J, Filoche M, White J, Takayama S, Grotberg JB.Biomicrofluidics201526392827
MicrofluidicsControlled cellular microenvironmentCell, isoform, and environment factors shape gradients and modulate chemotaxisChang SL, Cavnar SP, Takayama S, Luker GD, Linderman JJ.PLoS One201525909600
Hanging drop/3D cultureControlled cellular microenvironmentFormation of stable small cell number three-dimensional ovarian cancer spheroids using hanging drop arrays for preclinical drug sensitivity assaysRaghavan S, Ward MR, Rowley KR, Wold RM, Takayama S, Buckanovich RJ, Mehta G.Gynecol Oncol201525913133
NanochannelsDNA linearizationFracture fabrication of a multi-scale channel device that efficiently captures and linearizes DNA from dilute solutionsKim BC, Weerappuli P, Thouless MD, Takayama S.Lab Chip201525589471
MicrofluidicsMicro/nanofabricationSupersoft lithography: candy-based fabrication of soft silicone microstructuresMoraes C, Labuz JM, Shao Y, Fu J, Takayama S.Lab Chip201526245893
MicrofluidicsMicrofluidic circuitsMultiple independent autonomous hydraulic oscillators driven by a common gravity headKim SJ, Yokokawa R, Lesher-Perez SC, Takayama S.Nat Commun201526073884
Misc./CollabMisc.Shear-Triggered Crystallization and Light Emission of a Thermally Stable Organic Supercooled LiquidChung K, Kwon MS, Leung BM, Wong-Foy AG, Kim MS, Kim J, Takayama S, Gierschner J, Matzger AJ, Kim J.ACS Cent Sci201527162955
MicrofluidicsReproductive technologyRecent microfluidic devices for studying gamete and embryo biomechanicsLai D, Takayama S, Smith GD.J Biomech201525801423
ATPSBioassaysAqueous two-phase systems enable multiplexing of homogeneous immunoassaysSimon AB, Frampton JP, Huang NT, Kurabayashi K, Paczesny S, Takayama S.Technology (Singap World Sci)201425083509
ATPSBioassaysAqueous two-phase system patterning of detection antibody solutions for cross-reaction-free multiplex ELISAFrampton JP, White JB, Simon AB, Tsuei M, Paczesny S, Takayama S.Sci Rep201424786974
ATPSBioassaysLabel-free direct visual analysis of hydrolytic enzyme activity using aqueous two-phase system droplet phase transitionsLai D, Frampton JP, Tsuei M, Kao A, Takayama S.Anal Chem201424654925
ATPSBioprintingAqueous two-phase system technology for patterning bacterial communities and biofilmsDwidar M, Takayama S, Mitchell RJ.Methods Mol Biol201424664823
Hanging drop/3D cultureControlled cellular microenvironmentTransfer, imaging, and analysis plate for facile handling of 384 hanging drop 3D tissue spheroidsCavnar SP, Salomonsson E, Luker KE, Luker GD, Takayama S.J Lab Autom201424051516
MicrofluidicsControlled cellular microenvironmentDefined topologically-complex protein matrices to manipulate cell shape via three-dimensional fiber-like patternsMoraes C, Kim BC, Zhu X, Mills KL, Dixon AR, Thouless MD, Takayama S.Lab Chip201424632936
NanochannelsControlled cellular microenvironmentOne-dimensional patterning of cells in silicone wells via compression-induced fractureDixon AR, Moraes C, Csete ME, Thouless MD, Philbert MA, Takayama S.J Biomed Mater Res A201423733484
MicrofluidicsMicro/nanofabricationElevating samplingLabuz JM, Takayama S.Lab Chip201424781100
MicrofluidicsMicro/nanofabricationMicrofluidic device capable of medium recirculation for non-adherent cell cultureDixon AR, Rajan S, Kuo CH, Bersano T, Wold R, Futai N, Takayama S, Mehta G.Biomicrofluidics201424753733
NanochannelsMicro/nanofabricationThe Control of Crack Arrays in Thin FilmsHuang J, Kim BC, Takayama S, Thouless MD.J Mater Sci201431507306
NanochannelsMicro/nanofabricationFracture-based micro- and nanofabrication for biological applicationsKim BC, Moraes C, Huang J, Thouless MD, Takayama S.Biomater Sci201424707353
NanochannelsMicro/nanofabricationFracture-based fabrication of normally closed, adjustable, and fully reversible microscale fluidic channelsKim BC, Moraes C, Huang J, Matsuoka T, Thouless MD, Takayama S.Small201424942855
MicrofluidicsMicrofluidic circuitsControl of soft machines using actuators operated by a Braille displayMosadegh B, Mazzeo AD, Shepherd RF, Morin SA, Gupta U, Sani IZ, Lai D, Takayama S, Whitesides GM.Lab Chip201424196070
MicrofluidicsMicrofluidic circuitsPumps for microfluidic cell cultureByun CK, Abi-Samra K, Cho YK, Takayama S.Electrophoresis201423893649
ATPSBioassaysPreprogrammed, parallel on-chip immunoassay using system-level capillarity controlKim SJ, Paczesny S, Takayama S, Kurabayashi K.Anal Chem201323789820
NanochannelsBioassaysSuper-resolution imaging of PDMS nanochannels by single-molecule micelle-assisted blink microscopyCheng MC, Leske AT, Matsuoka T, Kim BC, Lee J, Burns MA, Takayama S, Biteen JS.J Phys Chem B201323256598
ATPSBioprintingDehydrated aqueous two-phase system micro-domains retain their shape upon rehydration to allow patterned reagent delivery to cellsBathany C , Park J , Cho YK , Takayama S .J Mater Chem B201332260986
ATPSBioprintingPatterning bacterial communities on epithelial cellsDwidar M, Leung BM, Yaguchi T, Takayama S, Mitchell RJ.PLoS One201323785519
ATPSBioprintingMicroscale determination of aqueous two phase system binodals by droplet dehydration in oilKojima T, Takayama S.Anal Chem201323614634
ATPSBioprintingDelivery of proteases in aqueous two-phase systems enables direct purification of stem cell colonies from feeder cell co-cultures for differentiation into functional cardiomyocytesFrampton JP, Shi H, Kao A, Parent JM, Takayama S.Adv Healthc Mater201323592706
ATPSBioprintingPatchy surfaces stabilize dextran-polyethylene glycol aqueous two-phase system liquid patternsKojima T, Takayama S.Langmuir201323581424
ATPSBioprintingCell co-culture patterning using aqueous two-phase systemsFrampton JP, White JB, Abraham AT, Takayama S.J Vis Exp201323567187
MicrofluidicsControlled cellular microenvironmentMicrofluidic interrogation and mathematical modeling of multi-regime calcium signaling dynamicsJovic A, Wade SM, Neubig RR, Linderman JJ, Takayama S.Integr Biol (Camb)201323732791
ATPSControlled cellular microenvironmentAqueous two-phase printing of cell-containing contractile collagen microgelsMoraes C, Simon AB, Putnam AJ, Takayama S.Biomaterials201324034500
ATPSControlled cellular microenvironmentProductive chemical interaction between a bacterial microcolony couple is enhanced by periodic relocationByun CK, Hwang H, Choi WS, Yaguchi T, Park J, Kim D, Mitchell RJ, Kim T, Cho YK, Takayama S.J Am Chem Soc201323316688
MicrofluidicsControlled cellular microenvironmentOn being the right size: scaling effects in designing a human-on-a-chipMoraes C, Labuz JM, Leung BM, Inoue M, Chun TH, Takayama S.Integr Biol (Camb)201323925524
MicrofluidicsControlled cellular microenvironmentMicrofluidic systems: a new toolbox for pluripotent stem cellsLesher-Perez SC, Frampton JP, Takayama S.Biotechnol J201323125055
Misc./CollabControlled cellular microenvironmentLocalized micro-scale disruption of cells using laser-generated focused ultrasoundBaac HW, Frampton J, Ok JG, Takayama S, Guo LJ.J Biophotonics201323420806
NanochannelsDNA LinearizationMicro- and nanofluidic technologies for epigenetic profilingMatsuoka T, Choul Kim B, Moraes C, Han M, Takayama S.Biomicrofluidics201323964309
MicrofluidicsMicro/nanofabricationSimple Multi-level Microchannel Fabrication by Pseudo-Grayscale Backside Diffused Light LithographyLai D, Labuz JM, Kim J, Luker GD, Shikanov A, Takayama S.RSC Adv201324976950
MicrofluidicsMicro/nanofabricationPreprogrammed capillarity to passively control system-level sequential and parallel microfluidic flowsKim SJ, Paczesny S, Takayama S, Kurabayashi K.Lab Chip201323598742
MicrofluidicsMicro/nanofabricationLarge-scale, ultrapliable, and free-standing nanomembranesKang E, Ryoo J, Jeong GS, Choi YY, Jeong SM, Ju J, Chung S, Takayama S, Lee SH.Adv Mater201323423854
NanochannelsMicro/nanofabricationGuided fracture of films on soft substrates to create micro/nano-feature arrays with controlled periodicityKim BC, Matsuoka T, Moraes C, Huang J, Thouless MD, Takayama S.Sci Rep201324149668
MicrofluidicsMicrofluidic circuitsMicrofluidic oscillators with widely tunable periodsKim SJ, Yokokawa R, Takayama S.Lab Chip201323429765
MicrofluidicsMisc.Room temperature phosphorescence of metal-free organic materials in amorphous polymer matricesLee D, Bolton O, Kim BC, Youk JH, Takayama S, Kim J.J Am Chem Soc201323521108
MicrofluidicsReproductive TechnologyExternal mechanical cues trigger the establishment of the anterior-posterior axis in early mouse embryosHiramatsu R, Matsuoka T, Kimura-Yoshida C, Han SW, Mochida K, Adachi T, Takayama S, Matsuo I.Dev Cell201324176640
ATPSControlled cellular microenvironmentAqueous two-phase system-derived biofilms for bacterial interaction studiesYaguchi T, Dwidar M, Byun CK, Leung B, Lee S, Cho YK, Mitchell RJ, Takayama S.Biomacromolecules201222793044
NanochannelsDNA LinearizationNanoscale squeezing in elastomeric nanochannels for single chromatin linearizationMatsuoka T, Kim BC, Huang J, Douville NJ, Thouless MD, Takayama S.Nano Lett201223186544
MicrofluidicsMicro/nanofabricationAnalyzing threshold pressure limitations in microfluidic transistors for self-regulated microfluidic circuitsKim SJ, Yokokawa R, Takayama S.Appl Phys Lett201223284181
MicrofluidicsMicro/nanofabricationMicrofluidic automation using elastomeric valves and droplets: reducing reliance on external controllersKim SJ, Lai D, Park JY, Yokokawa R, Takayama S.Small201222761019
MicrofluidicsReproductive TechnologyLab-on-a-chip biophotonics: its application to assisted reproductive technologiesLai D, Smith GD, Takayama S.J Biophotonics201222700221