The Takayama Lab is educationally affiliated with the Coulter Department of Biomedical Engineering (BME). Our lab is physically located within the Krone Engineered Biosystems Building (EBB).
We construct organs-on-a-chip systems to dissect cell signaling pathways, understand disease physiology, test therapeutics, and perform cell-based therapies. Tunable nanofluidic systems are used to perform multi-color histone mapping of single strands of chromatin. And aqueous two phase systems (ATPS) micropatterning enables cell printing and droplet-based bioassays.
Examples of specific projects include: Microfluidic models of cancer metastasis, Lung-on-a-chip, In vitro fertilization on a chip, Phase locking analysis in GPCR signaling, and Validation of protein biomarkers of disease for development of diagnostics.